| David-Désiré Pollonnais - Mayor of Villefranche-sur-Mer | Acquire the estate in the 19th century. |
| Léopold II - King of Belgians | Expands the estate and launches the gardens. |
| Aaron Messiah - Architect | Take over the villa for Leopold II. |
| Elie Lainé - Landscape | Created the landscape garden in 1905. |
| Jules Vacherot - Landscape architect | Set up the Northeast Garden. |
| Alexandre Marnier-Lapostolle - Owner and patron | Developed the botanical garden in 1924. |
| Julien Marnier-Lapostolle - Botanist and owner | Turns the site into a global conservatory. |
| Suzanne Marnier-Lapostolle - Wife of Julien | Continues the development after 1976. |
| Guy Joulin - Landscape | Redesign of greenhouses (1988-1999). |