| Bruno de Cologne (saint Bruno) - Founder of the Order | Set up the first community in 1084. |
| Hugues de Grenoble - Bishop and protector | Guida Bruno and ratified the donation. |
| Guigues - Prior and legislator | Author of the Cartuses* (1127). |
| Dom Innocent Le Masson - Reconstructor of the seventeenth century | Rebuilt the monastery after 1676. |
| Dom Nicolas-Albergati de Geoffroy - Last prior before 1792 | Left the monastery under the Revolution. |
| Dom Dysmas de Lassus - Current Minister General (since 2014) | Prior elected after François-Marie Velut. |
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