| Humbertus de Brina - First known tutor | Mentioned in 1298, presumed founder. |
| Jean d’Orlier - Preceptor in the 15th century | Initiator of reconstructions and artistic sponsors. |
| Guido Guersi - Preceptor successor | Continues works and orders of works. |
| Martin Schongauer - Associate Artist | Created works for preceptory. |
| Mathias Grünewald - Painter of the Issenheim table | Major work commissioned for the church. |
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