| Guillaume de Melun - Archbishop of Sens (XIVth century) | Acquiert the hotel of Hesomesnil in 1366. |
| Tristan de Salazar - Archbishop of Sens (1474-1519) | Rebuilt the hotel between 1495 and 1519. |
| Marguerite de Valois - Queen of France ("Queen Margot") | Residence at the hotel in 1605-1606. |
| Nostradamus - Astrologer and doctor | Accommodation at the hotel in 1555. |
| Antoine Du Prat - Archbishop and Chancellor of France | Busy hotel under François I. |
| Charles V - King of France (1364-1380) | Exchange a hotel for Melun's. |
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