| Brice Bauderon de Senecé - Founder and lawyer | Builder of the hotel around 1652, lieutenant-general in Mâcon. |
| Pierre Desvignes de Davayé - First Mayor of Mâcon | Acquiert the hotel in 1698, husband of Jeanne Bauderon. |
| Jeanne Bauderon - Hotel heiress | Brice Bauderon's daughter married Pierre Desvignes in 1695. |
| Abel Jean Baptiste Desvignes - Mayor and Deputy | Redesigning the hotel in the 19th century with revolutionary allowances. |
| Antoine Alphonse Desvignes - Last owner Desvignes | Turns the hotel into a hospital in 1870, dies typhus. |
| Pierre-Abel Desvignes - Noble and military | Modernise the hotel between 1772 and 1778. |
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