| Jacques Groslot - Bailli d'Orléans and Chancellor | Sponsor and first owner. |
| François II - King of France | Died in the hotel in 1560. |
| Catherine de Médicis - Regent of France | Stayed during the regency. |
| Charles IX - King of France | Stayed there in 1560 and 1573. |
| André Delton - Architect of Historic Monuments | Directs the restoration in the 19th. |
| Ambroise Paré - Royal surgeon | Present at the death of Francis II. |
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