| Salomon James de Rothschild - Baron and collector | Son of James, founder of the Parisian branch. |
| Adèle von Rothschild (baronne Adèle) - Spouse of Solomon, patron | Hotel sponsor and State donor. |
| Léon Ohnet - Initial architect | Died in 1874 during the works. |
| Justin Ponsard - Successor architect | Construction was completed in 1878. |
| Léopold Moulignon - Decorative painter | Author of Italy-inspired interior decorations. |
| Paul Doumer - President of the Republic | Murdered in the hotel in 1932. |
| Rose Valland - Conservant and resistant | Worked in the art recovery department. |