| Jacques Cartier - Explorer and owner | Lived and transformed the mansion (1541-1557). |
| François Ier - King of France | Sponsor of Cartier's trips to Canada. |
| Catherine des Granches - Wife of Cartier | He lived there until 1557. |
| David M. Stewart et Liliane Stewart - Patrons and restaurateurs | Buyers and donors of the mansion (1978-2012). |