| Jean XXII - Pope (1316–1334) | Created the diocese of Lombez. |
| Arnaud Roger - First Bishop of Lombez (1317–1328) | The building of the cathedral was launched. |
| Jacques Colonna - Bishop of Lombez (1328–1341) | Friend of Petrarch, supervised the works. |
| Pétrarque - Italian poet | Honorary Chanoine in 1330. |
| Guillaume de Durfort - Bishop of Lombez (died 1378) | Funeral room in the southern chapel. |
| Arnaud de Moles - Master glassmaker | Suspected author of stained glass (XVth–XVIth). |
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