| Jacques de Beaujeu-Amplepuis - Counselor and king's chamberlain | Lord of the castle, husband of Jacqueline Jouvenel |
| Jacques de Beaune - Baron de Semblançay and Mayor of Tours | Owner influential under François I |
| Jacques Gaultier de Brûlon (père et fils) - Treasurers of France and Mayors of Tours | Family owner in the 17th-18th century |
| Gabriel de Razilly - Knight of Malta and lieutenant of the king | Last lords before transformations |
| Laurent d'Allard - Artillery commissioner, knight of Saint-Louis | Owner in the 18th century |